Use Trap Cards to restrict the movements of your opponent, then once the times right, Xyz Summon Number 39: Utopia Double, then attack with Utopia to seize victory.
However, modern sets are still phenomenally expensive at times
Taking an artifact or creature card means it hurts the majority of cards in the set, so you shouldnt miss very often
There are 15 Autobots and Decepticons represented here, all appearing at Mythic rarity, so theres no reason to expect that Optimus Prime will be harder to get ahold of than say, Slicer (other than fan favoritism, of course)
Fusion Strike is one of the biggest expansions of the Pokemon TCG, making it rough to pull any particular card you want
Hopefully, if youre playing against it, their security is completely dead