Because Curse costs 5 mana, you need to run it alongside cheaper answers to Infect
6E Classic Sixth Edition 60 - Uncommon - English "Temper, temper." Ertai, wizard adept Commander, Legacy, Vintage Alchemy, Brawl, Competitive Brawl, Historic, Modern, Pauper, Pioneer, Standard, Timeless
Build Your Ultimate Deck: Inside this booster box, you'll find a plethora of cards, including powerful allies, devastating spells, and game-changing artifacts
Then there is the nice calm 4/4 flying dragon for a mere two loyalty cost
(Damage causes loss of life.) Illustrated by Josh Hass Standard Not Legal Alchemy Not Legal Pioneer Not Legal Historic Not Legal Modern Not Legal Brawl Not Legal Legacy Legal Comp
Spending your wildcards carefully allows you to try a variety of ways to play the game