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To fully capitalize on Infusion and similar payoffs, such as Pest Mascot, you will want to pack your deck with a steady stream of life gain effects

The land base is vast and plentiful - especially with shock lands, triomes, and one of the best Evolving Wilds -like lands: Fabled Passage

Even then, such cards are terrible once the Serpent tokens land, so theres not a perfect solution

With them, you can get an idea of how much your cards are worth

Why is it one mana

In the rare cases that Ive seen this card in Commander, its usually been played with something like Nyxbloom Ancient to create a ridiculous amount of mana that almost invariably wins the game on the spot