Even when the combo is only two cards, neither one of them start in a zone where you can always find them and the opponent can interact by killing either the Enchantment or the Creature
One of the best enchantments you can play with Isshin is Angelic Exaltation, which gives a creature +X/+X when a creature you control attacks alone, with X being equal to the number of creatures you control
So, we have a deck that can go wide and go tall, depending on our needs
Chaos Orb breaks the rules by literally making contact with other cards, then taking them out of the battlefield in the process
If you do, its sacrificed when it enters.) Its emotions run high
As a result, it's often better to let an attack through rather than risk losing Prosper to a post-combat removal spell or combat trick