![Thalidomide-5-OH Size:2mg solid Chemical Name: 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11557_1622698279.gif?v=1628664514)
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Chemical Name: 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide
The IC50 value for inhibition of PI3Kα by Pilaralisib (XL147) is determined at various concentrations of ATP
Smiles: CC1C(=CC=C(C#N)C=1Cl)N1[C@H]2CC(C)(O)C[C@H]1CC2
InChi: InChI=1S/C22H27N3O3S/c1-25-20-8-3-15(21-13-23-14-29-21)11-18(20)19(12-22(25)26)24-16-4-6-17(7-5-16)28-10-9-27-2/h3
Stypinski D
Thalidomide-5-OH Size:2mg solid Chemical Name: 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamideThalidomide 5 OH is the Thalidomide based cereblon ligand used in the recruitment of CRBN protein. Thalidomide 5 OH can be connected to the ligand for protein by a linker to form PROTACs. Product information CAS Number: 64567 60 8 Molecular Weight: 274. 23 Formula: C13H10N2O5 Chemical Name: 2 (2, 6 dioxopiperidin 3 yl) 5 hydroxy 2, 3 dihydro 1H isoindole 1, 3 dione Smiles: OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: LJBQRRQTZUJWRC UHFFFAOYSA N