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The deck is mono-white, but many elements can be applied elsewhere, though especially life-gain and pillow-fort decks

But this card is almost never played for Life and we know it

Thus, I would maindeck it if, and only if, non-interactive combo isnt very popular

Laser-Focused on Noncreature Spells Unlike the catch-all Force of Will, Negation specifically counters only non-creature spells - instants, sorceries, enchantments, and planeswalkers

It costs a lot of mana but lets you storm off in the late game if you have Lessons in your graveyard along with a cost reducer like Goblin Electromancer

But that doesnt mean theres not plenty of room for improvement