Three Arrows is a three-cost action that deals two damage to one character and another one damage to another
Luckily there are planeswalkers on hand to fight against this corruption: Elspeth (Remember her from Alara?) Venser (A new guy from Urborg), and home-grown hero Koth the Hammer are present to help stem the tide of corruption (Also Tezzeret is there I guess, but hes not gonna help because hes an A-hole)
As if that wasnt enough, Yugis deck also has playable versions of the three Egyptian God Cards, Slifer, Obelisk and Ra
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Free spells like Force of Negation would give it a bit of insulation from interaction, and I expect modern day versions would look and act similarly to Living End, albeit with a much more powerful end game
Tribute Mage, Fabricate, and, appropriately, Gamble become must-plays when your deck's in need of the Thumb