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5R)-2-(hydroxymethyl)-5-{6-[(2-phenylethyl)amino]-9H-purin-9-yl}oxolane-3
CAS Number: 1443290-89-8
5-10 mM in cell culture
After being fasted for 18 h
35 mg/mL (14
SK1-I 755OV-216 303 Free Base 5R)-2-(hydroxymethyl)-5-{6-[(2-phenylethyl)amino]-9H-purin-9-yl}oxolane-3SK1 I (BML 258), an analog of sphingosine, is an isozyme specific competitive SPHK1 inhibitor with a Ki value of 10 M. SK1 I shows no activity at SPHK1 PKC, PKC, PKA, AKT1, ERK1, EGFR, CDK2, IKK or CamK2. SK1 I enhances autophagy and has antitumor activity. Product information CAS Number: 1072443 89 0 Molecular Weight: 313. 86 Formula: C17H28ClNO2 Chemical Name: 2 (methylamino) 5 (4 pentylphenyl)pent 4 ene 1,3 diol hydrochloride Smiles: Cl.
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