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but has little effect on the basal level of proliferation
so it has IC50 >1 µM for inhibiting demthylation of H3K4 in U2OS human osteosarcoma cell line and in human breast adenocarcinoma MCF7 tumor cell proliferation assay
31(6):712-22
CAS Number: 434-03-7
Formula: C16H10O7
Fezolinetant olimod hydrochloride but has little effect onFezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. Product information CAS Number: 1629229 37 3 Molecular Weight: 358. 39 Formula: C16H15FN6OS Chemical Name: 5 [(8R) 7 (4 fluorobenzoyl) 8 methyl 5H,6H,7H,8H [1,2,4]triazolo[4,3 a]pyrazin 3 yl] 3 methyl 1,2,4 thiadiazole Smiles: CC1N=C(SN=1)C1=NN=C2[C@@H](C)N(CCN12)C(=O)C1C=CC(F)=CC=1 InChiKey: PPSNFPASKFYPMN SECBINFHSA N InChi: InChI=1S
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