However, if a single creature with lifelink deals combat damage to multiple creatures, players, and/or planeswalkers at the same time (perhaps because it has trample or was blocked by more than one creature), the ability will trigger only once
Still, once it resolves, you can choose how to kill your opponent slowly by either casting spells from the top of their library without paying mana, shrinking their hand, killing their creatures, and, if they've survived long enough, exiling all their non-land permanents with the ultimate
One of the longstanding tricks in the format is to play Karmic Guide alongside Saffi Erikdottir so that you can put the echo trigger on the stack and then sacrifice Saffi, eventually bringing back Karmic Guide (since, in your Karador deck, Saffi is cheaper to cast)
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Even when it kills the creatures
Additionally, figuring out how many Pirates we needed and which Vampires were most important was more challenging than expected