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resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death
24(6):791-805
The inhibitory activity of MGCD0103 reaches the maximum plateau at 6 μM
4-fluoro-5-methyl-
InChiKey: KZJWDPNRJALLNS-VJSFXXLFSA-N
10-Deacetylbaccatin III 60106 resulting in DNA breaks that10 Deacetylbaccatin III, also known as 10 DAB or 10 DAB III, is a closely related natural organic compounds isolated from dried needles and small branches of the European yew tree (Taxus baccata). 10 Deacetylbaccatin III is a precursor to the anti cancer drug docetaxel (Taxotere). pacitaxel (taxol); cabazitaxel. 10 10 deacetylbaccatin III was found to selectively inhibit the growth of L. DONOVANI intracellular amastigotes within J774 murine
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