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preliminary results
Mean clearance (CL) and volume of distribution at steady state (Vss) following iv administration are 39±11 (mL/min)/kg and 1
Probe compound mL098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides
CAS Number: 1595129-71-7
ABC294640 demonstrates dose-dependent inhibition of SK2 with an IC50 of approximately 60 μM without affecting the activity of SK1 at concentrations up to at least 100 μM
(R)-(-)-Rolipram Trifluoro-1-(thiophen-2-yl)-2-(2-(m-tolyl)hydrazono)butane-1 3-dione preliminary results(R) ( ) rolipram R enantiomer of rolipram is a potent and cAMP specific PDE4 inhibitor with IC50 of 022 M and 25 fold more potent than rolipram IC50 258 M in inhibiting membrane bound PDE 4 Product information CAS Number: 85416 75 7 Molecular Weight: 275. 34 Formula: C16H21NO3 Synonym: (R) Rolipram ( ) Rolipram Chemical Name: (4R) 4 [3 (cyclopentyloxy) 4 methoxyphenyl]pyrrolidin 2 one Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1 InChiKey: