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Mechanistic studies revealed that NSC319726 restores WT structure and function to the p53R175 mutant
In H4 cells expressing the mCherry-GFP-LC3 reporter PIK-III inhibits the formation of mCherry-positive autolysosomes and increases the cytosolic signal of LC3 under basal conditions and when autophagy is induced with the mTOR inhibitor AZD8055
InChiKey: DAZSWUUAFHBCGE-KRWDZBQOSA-N
InChi: InChI=1S/C26H22Cl2N4O3/c1-5-21(33)30-18-8-6-7-14(2)25(18)32-26-29-13-16-11-15(9-10-17(16)31-26)22-23(27)19(34-3)12-20(35-4)24(22)28/h5-13H
a protein that plays an important role in fungal cell wall integrity
SNS-032 Catalog No.:M7780-2 Mechanistic studies revealed that NSC319726SNS 032 (BMS 387032) is a potent and selective inhibitor of CDK2, CDK7, and CDK9 with IC50s of 38 nM, 62 nM and 4 nM, respectively. SNS 032 has antitumor effect. Product information CAS Number: 345627 80 7 Molecular Weight: 380. 53 Formula: C17H24N4O2S2 Synonym: SNS 032 SNS032 BMS387032 BMS 387032 BMS 387032 Related CAS Number: 345627 90 9 (SNS 032 hydrochloride) Chemical Name: N (5 {[(5 tert butyl 1, 3 oxazol 2 yl)methyl]sulfanyl} 1, 3 thiazol 2
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