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to overcome resistance caused by β-lactamases
aeruginosa infections was caused by an exuberant neutrophil response stimulated by 3-O-C12-HSL-induced IL-8
It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase-1
COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCC4C5=CC=CC=C5NC=4[C@@H]3C[C@@H]21
Chemical Name: 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol hydrochloride
MG-277 164015 to overcome resistance caused byMG 277, a molecular glue degrader, effectively induces degradation of a translation termination factor, GSPT1, with a DC50 of 1. 3 nM. MG 277 potently inhibits tumor cell growth in a p53 independent manner, with IC50s of 3. 5 nM for RS4; 11 cells and 3. 4 nM for p53 mutant RS4; 11 IRMI 2 cells, respectively. Anticancer activity. Product information CAS Number: 2411085 89 5 Molecular Weight: 774. 71 Formula: C41H42Cl2FN5O5 Chemical Name: (3'R,4'S,5'R)
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