Picroside II xamethonium Bromide MDA-MB-453 and MDA-MB-231 cell lines

MDA-MB-453 and MDA-MB-231 cell lines with an IC50 close to 100 μM

5% propylene glycol

InChiKey: PHHZKBMVRPULAW-UHFFFAOYSA-N

Woessner R

Real-time PCR results indicate that incubation of RAW264

Picroside II xamethonium Bromide MDA-MB-453 and MDA-MB-231 cell linesPicroside II, an iridoid compound extracted from Picrorhiza, exhibits anti inflammatory and anti apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF B pathways. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood brain barrier (BBB) after cerebral ischemia