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In acute toxicity studies in mice
GW788388 (50 mg/kg/day
56(2):427-36
Chemical Name: ethyl 12-azido-8-methyl-9-oxo-2
BC(bladder compliance)
Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C In acute toxicity studies inEGFR (epidermal growth factor receptor) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor . EGFR dimerization stimulates its intrinsic intracellular protein tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues on the C terminal domain of EGFR occurs. These include Y992, Y1045, Y1068, Y1148 and Y1173. This
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