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C[C@@]1(CCCN1)C1NC2C(=CC=CC=2C(N)=O)N=1
and blocks proliferation and induces apoptosis in CML cell lines
Bugarski D
GS-9876 inhibits IC-stimulated TNFα and IL-1β release (EC50=121±77 nM and 9±17 nM
Molecular Weight: 424
Tacrolimus Catalog No.:M7733-10 C[C@@]1(CCCN1)C1NC2C(=CC=CC=2C(N)=O)N=1Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T lymphocyte signal transduction and IL 2 transcription. Immunosuppressive properties. Product information CAS Number: 104987 11 3 Molecular Weight: 804. 02 Formula: C44H69NO12 Synonym: FK 506 FK 506 FK506 fujimycin Prograf Protopic Advagraf Astagraf XL Related CAS Number: 109581 93 3
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