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AZ-5104 was identified to exhibit 5-fold potency compared to AZD-9291
5)26(25)11-13-44(27
ascomyceticus
8(10):839-47
Chemical Name: 2-hydroxy-3-[(1r
Marinopyrrole A ticasone (propionate) AZ-5104 was identified to exhibitMarinopyrrole A (Maritoclax) is a selective Mcl 1 antagonist. It binds to Mcl 1, but not Bcl XL, and targets Mcl 1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl 1 with an IC50 of 10. 1 M. Product information CAS Number: 1227962 62 0 Molecular Weight: 510. 15 Formula: C22H12Cl4N2O4 Chemical Name: 2 [4,4',5,5' tetrachloro 2' (2 hydroxybenzoyl) 1'H [1,3' bipyrrole] 2 carbonyl]phenol Smiles:
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