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IWR-1 exerts its effect via interaction with Axin
Chemical Name: N-(5-tert-butyl-3-methanesulfonamido-2-methoxyphenyl)-2-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}-2-oxoacetamide hydrochloride
1173111-67-5 (PF-04929113 mesylate)
isosilibinin
In an intracellular Ca2+ (iCa2+) mobilization assay using HT29 colon cancer cells
Pep2m, myristoylated TFA ithocholic acid IWR-1 exerts its effect viaPep2m, myristoylated TFA (Myr Pep2m TFA) is a cell permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase (PKM) downstream targets, N ethylmaleimide sensitive factor glutamate receptor subunit 2 (NSF GluR2) interactions. PKM is an autonomously active isozyme of protein kinase C (PKC). Product information Molecular Weight: 1497. 81 Formula: C65H119F3N18O16S Synonym: Myr Pep2m TFA Chemical Name: (2S, 5S, 8S, 11S, 14S, 17S, 20S, 23S,