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A839977 is a P2X7R antagonist
SB-705498 inhibits the capsaicin-
Smiles: CCCC[C@H](NC(=O)CN1CCC(CC1)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](CC2=CNC3=CC=CC=C23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CC2C=CC=CC=2)NC(=O)[C@H](CC2=CN=CN2)NC1=O)C(N)=O
2012 Jun 4
Torin1 (250 nM) completely inhibits proliferation and causes a G1/S cell cycle arrest
Niraparib (R-enantiomer) 026S R S)-AHPC-C4-NH2 dihydrochloride A839977 is a P2X7R antagonistNiraparib R enantiomer (MK 4827 R enantiomer) is an excellent PARP1 inhibitor with IC50 of 2. 4 nM. Product information CAS Number: 1038915 58 0 Molecular Weight: 320. 39 Formula: C19H20N4O Chemical Name: 2 {4 [(3R) piperidin 3 yl]phenyl} 2H indazole 7 carboxamide Smiles: NC(=O)C1=CC=CC2=CN(N=C21)C1C=CC(=CC=1)[C@@H]1CNCCC1 InChiKey: PCHKPVIQAHNQLW AWEZNQCLSA N InChi: InChI=1S C19H20N4O c20 19(24)17 5 1 3 15 12 23(22 18(15)17)16 8 6 13(7 9 16)14 4 2 10
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