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induces liver damage
Jeanfavre DD
At the 1 mg/kg dose CC-115 shows significant inhibition at 1 and 3 hours
PubMed PMID: 27011212
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Rucaparib phosphate - CAS# 459868-92-9 e (disodium pentahydrate) induces liver damageRucaparib is a tricyclic indole poly(ADP Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1 mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. Product information CAS Number: 459868 92 9 Molecular Weight: 421. 36 Formula: C19H21FN3O5P Synonym: AG014699
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