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Cellular activity of Avapritinib on KIT D816 mutants is measured by autophosphorylation in the human mast cell leukemia cell line HMC1
AG1 increases GSH levels and reduced ROS levels together with increased G6PD activity under these drug-induced oxidative stress
RIN1 inhibits the proliferation of hematologic cancer cell lines and promoted skeletal muscle diferentiation from C2C12 myoblasts
EPZ-6438 was used at 1 µM final concentration in vitro and in cellular assays
providing significant differences from 1 to 2 h
diethyl (5-methanesulfonamido-2-nitrophenyl)phosphonate Catalog No.:M35077-C Cellular activity of Avapritinib onProduct information Molecular Weight: 352. 30 Formula: C11H17N2O7PS Smiles: CS(=O)(=O)NC1=CC(=C(C=C1)[N+]([O ])=O)P(=O)(OCC)OCC InChiKey: HVMDGBIFBBQONK UHFFFAOYSA N InChi: InChI=1S C11H17N2O7PS c1 4 19 21(16,20 5 2)11 8 9(12 22(3,17)18)6 7 10(11)13(14)15 h6 8,12H,4 5H2,1 3H3 Technical Data Appearance: Solid Power Purity: 95% (or refer to the Certificate of Analysis) Solubility: To be determined Shipping Condition: Shipped under ambient temperature as
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