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Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism
Smiles: CN1C(=NC2=CC=CC=C12)C1C=C2C(N=C(CCC)N2CC2=CC=C(C=C2)C2=CC=CC=C2C(O)=O)=C(C)C=1
InChiKey: TVQZAMVBTVNYLA-UHFFFAOYSA-N
Te Poele RH
SB505124 susspresses CTGF and α-SMA observed by immunofluorescence
Istaroxime Catalog No.:M9594-10 Inhibition of NAALADase by 2-PMPAIstaroxime, also known as PST 2744, is a positive inotropic agent that mediates its action through inhibition of sodium potassium adenosine triphosphatase (Na+ K+ ATPase). Na+ K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy