Sitagliptin-d4 phosphate 15528 as a free base) produces

as a free base) produces a statistically significant number of 60-day survivors (curative effect) in mice with IP implanted L1210 leukemia

but with no such inhibition on MDA-MB-468 (IC50

CAS Number: 1953-02-2

InChi: InChI=1S/C10H13N/c1-8-6-7-11-10-5-3-2-4-9(8)10/h6-7H

F420 is biosynthesized in Methanocaldococcus jannaschii by the action of eight enzymes with the formation of the deazaflavin chromophore (Fo) as the remaining unsolved step

Sitagliptin-d4 phosphate 15528 as a free base) producesSitagliptin d4 (MK 0431 d4) phosphate is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK 0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco 2 cell extracts. Product information CAS Number: 1432063 88 1 Molecular Weight: 508. 33 Formula: C16H17F6N5O5P Chemical Name: (3R) 3 amino 1 [3 (trifluoromethyl)(5,5,6,6 H) 5H,6H,7H,8H [1,2,4]triazolo[4,3 a]pyrazin 7 yl] 4 (2,4,5 trifluorophenyl)butan 1 one