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Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy
2010 Dec 23
and its Ki value is 6
a selective MT1/MT2 receptor agonist
MM-102 (HMTase Inhibitor IX) has IC50=25 μM in both cell lines and completely inhibits cell growth in these cell lines at 75 μM
Hydroxyurea Size:Solid 2 mg Pharmacological inhibition of ULK1 kinaseHydroxyurea is a fetal hemoglobin stimulator and ribonucleotide reductase inhibitor used to treat sickle cell anemia, myeloproliferative disorders, and leukemias. It decreases the production of deoxyribonucleotides and also increases levels of NO in the blood. Product information CAS Number: 127 07 1 Molecular Weight: 76. 05 Formula: CH4N2O2 Chemical Name: hydroxyurea Smiles: NC(=O)NO InChiKey: VSNHCAURESNICA UHFFFAOYSA N InChi: InChI=1S CH4N2O2 c2
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