YO-01027 I-IN-1 InChi: InChI=1S/C31H42O17/c1-3-16-17(18(28(41)42-2)12-45-29(16)48-31-27(40)24(37)22(35)19(11-32)46-31)10-21(34)44-13-20-23(36)25(38)26(39)30(47-20)43-9-8-14-4-6-15(33)7-5-14/h3-7

InChi: InChI=1S/C31H42O17/c1-3-16-17(18(28(41)42-2)12-45-29(16)48-31-27(40)24(37)22(35)19(11-32)46-31)10-21(34)44-13-20-23(36)25(38)26(39)30(47-20)43-9-8-14-4-6-15(33)7-5-14/h3-7

VER155008 also decreases amyloid plaques and PHF-tau associated with amyloid plaques in 5XFAD mice

InChiKey: HSTZMXCBWJGKHG-CUYWLFDKSA-N

InChi: InChI=1S/C58H70F3N9O9/c1-39(62-2)53(71)68-51(42-18-10-5-11-19-42)57(75)70-29-13-22-48(70)55(73)69-52(50(40-14-6-3-7-15-40)41-16-8-4-9-17-41)56(74)64-28-31-77-33-35-78-34-32-76-30-27-63-54(72)44-21-12-20-43(36-44)47-37-49(66-38-65-47)67-45-23-25-46(26-24-45)79-58(59

Formula: C19H22FN3O3

YO-01027 I-IN-1 InChi: InChI=1S/C31H42O17/c1-3-16-17(18(28(41)42-2)12-45-29(16)48-31-27(40)24(37)22(35)19(11-32)46-31)10-21(34)44-13-20-23(36)25(38)26(39)30(47-20)43-9-8-14-4-6-15(33)7-5-14/h3-7YO 01027 (Dibenzazepine; DBZ) is a potent secretase inhibitor with IC50 values of 2. 92 and 2. 64 nM for Notch and APPL cleavage, respectively. Product information CAS Number: 209984 56 5 Molecular Weight: 463. 48 Formula: C26H23F2N3O3 Chemical Name: (2S) 2 [2 (3, 5 difluorophenyl)acetamido] N [(10S) 8 methyl 9 oxo 8 azatricyclo[9. 4. 0. 0, ]pentadeca 1(15), 2, 4, 6, 11, 13 hexaen 10 yl]propanamide Smiles: