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stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB)
4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile
InChi: InChI=1S/C24H38O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17
CAS Number: 129-46-4
ARM1 occupied the binding site for the ω-end of LTA4
Hydrocortisone hemisuccinate 414KF-82958 hydrobromide stabilizes G-quadruplexes (G4s) in cellsHydrocortisone hemisuccinate (Hydrocortisone 21 hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti inammatory drug (SAID). Hydrocortisone hemisuccinate inhibits proinflammatory cytokine activity, with IC50s of 6. 7 and 21. 4 M for IL 6 and IL 3, respectively. Hydrocortisone hemisuccinate can be used for the research of ulcerative colitis (UC). Product information CAS Number: 2203 97 6 Molecular Weight: 462. 53 Formula:
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