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Cytotoxicity of Senecio in macrophages is mediated via its induction of oxidative stress
N-dimethyl)-Amiloride (DMA) inhibited NHE1
5-h]isochromen-11-yl acetate
Approximately 1 month after treatment initiation
is a cereblon ligand with PEG linker and terminal acid for onward chemistry
Mal-amido-PEG4-acid 22231 Cytotoxicity of Senecio in macrophagesMal amido PEG4 C2 acid is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1263045 16 4 Molecular Weight: 416. 42 Formula: C18H28N2O9 Chemical Name: 1 [3 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)propanamido] 3,6,9,12 tetraoxapentadecan 15 oic acid Smiles: OC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O InChiKey: IAJVEYLYYHOZEY UHFFFAOYSA N InChi: InChI=1S C18H28N2O9 c21 15(3 6 20 16(22)1 2 17(20)23)19 5 8