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BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13
The combination of inhibitory activities on independent kinase and bromodomain oncogenic pathways exemplifies a new strategy for rational single-agent polypharmacological targeting
Tavaré JM
Molecular Weight: 310
but it showed only limited selectivity over mouse FFA1
TC-S 7001 - CAS# 867017-68-3 278 BCI specifically inhibits DUSP6 andTC S 7001, CAS No. 867017 68 3, is a potent and highly selective ROCK inhibitor. Product information CAS Number: 867017 68 3 Molecular Weight: 402. 79 Formula: C18H13ClF2N6O Synonym: Azaindole 1 ROCK IN 2 Chemical Name: 6 chloro N4 (3,5 difluoro 4 ((3 methyl 1H pyrrolo[2,3 b]pyridin 4 yl)oxy)phenyl)pyrimidine 2,4 diamine Smiles: CC1=CNC2=NC=CC(OC3C(F)=CC(=CC=3F)NC3=CC(Cl)=NC(N)=N3)=C21 InChiKey: NRSGWEVTVGZDFC UHFFFAOYSA N InChi: InChI=1S
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