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) inhibits XBP1 splicing in a model of ER stress in vivo
(2014) ACS Med
AZD2641 is currently in Phase I clinical study
resulting in increased recovery of transplantable HSCs
PubMed PMID: 16178722
RA-9 0296 ) inhibits XBP1 splicing inRA 9 is a cell permeable, potent and selective inhibitor of proteasome associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA 9 selectively induces apoptosis in ovarian cancer cell lines. Product information CAS Number: 919091 63 7 Molecular Weight: 365. 34 Formula: C19H15N3O5 Chemical Name: (3E,5E) 3,5 Bis[(4 nitrophenyl)methylene] 4 piperidinone Smiles: [O ][N+](=O)C1C=CC( C=C2\CNC
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