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BI-0252 y-4H-chromen-4-one the Ki is estimated to

SKU: 3871072128

4.5
USD100.00 USD140.00

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Description

the Ki is estimated to be 51

BI-0252 y-4H-chromen-4-one the Ki is estimated toBI 0252 is an orally active, selective MDM2 p53 inhibitor with an IC50 of 4 nM. BI 0252 can induce tumor regressions in all animals of a mouse SJSA 1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis. Product information CAS Number: 1818291 27 8 Molecular Weight: 566. 45 Formula: C30H26Cl2FN3O3 Chemical Name: 4 [(3S,3'S,3'aS,5'R,6'aS) 6 chloro 3' (3 chloro 2 fluorophenyl) 1' (cyclopropylmethyl)

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