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Ro 46-8443 is the first non-peptide Endothelin Receptor B selective antagonist with IC50 value of 110nM
3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzene-1-sulfonamide
and results in significant dose-dependent AVO induction and LC3-II stimulation in MIAPaCa-2 cells stably expressing a LC3-GFP construct
Oral administration yields similar concentrations of PQR-309 in brain and plasma samples illustrates that PQR-309 readily passes the blood–brain barrier
MSX-122 is a partial antagonist of CXCR4
Irinotecan Hydrochloride - CAS# 100286-90-6 dioside C Ro 46-8443 is the firstIrinotecan HCl a polymeric micellar preparation of S 38. Irinotecan Hydrochloride is the hydrochlorideN salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline based alkaloid extracted from the Asian tree Camptotheca acuminata. Product information CAS Number: 100286 90 6 Molecular Weight: 623. 14 Formula: C33H39ClN4O6 Synonym: CPT 11 hydrochloride CPT 11 hydrochloride CPT11 hydrochloride Camptothecin 11 hydrochloride Chemical Name:
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