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PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine is a potent small molecule

SKU: 30512979592

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Description

is a potent small molecule to selectively eliminate human pluripotent stem cells/hPSCs while sparing a large array of tissue-specific stem/progenitor and differentiated cells

BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM

KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion

InChi: InChI=1S/C22H24BrFN4O2

TAK-875 has no agonist potency to other members of the FFA receptor family with EC50 >10 μM

PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine is a potent small moleculePHA 767491, also known as CAY10572, is a potent, ATP competitive dual cdc7 cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. PHA 767491 Suppresses Hepatocarcinoma Synergistically with 5 Fluorouracil. PHA 767491 in combination with 5 FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP Ribose) polymerase

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