Indomethacin sodium hydrate - CAS# 74252-25-8 Catalog No.:M16485-C Smiles: COC1C=CC(Cl)=CC=1N(CC(=O)NC1=CC2OCOC=2C=C1)S(=O)(=O)C1C=CC=CC=1

Smiles: COC1C=CC(Cl)=CC=1N(CC(=O)NC1=CC2OCOC=2C=C1)S(=O)(=O)C1C=CC=CC=1

Solubility: DMSO 48 mg/mL (199

Formula: C44H88NO8P

is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities

Gregson SJ

Indomethacin sodium hydrate - CAS# 74252-25-8 Catalog No.:M16485-C Smiles: COC1C=CC(Cl)=CC=1N(CC(=O)NC1=CC2OCOC=2C=C1)S(=O)(=O)C1C=CC=CC=1Indomethacin sodium hydrate (Indometacin sodium hydrate) is a potent, blood brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX 1 and COX 2, respectively, in CHO cells. Indomethacin sodium hydrate disrupts autophagic flux by disturbing the normal functioning of lysosomes. Product information CAS Number: 74252 25 8 Molecular Weight: 433. 82 Formula: C19H21ClNNaO7 Chemical Name: sodium 2 [1 (4