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Cl-amidine hydrochloride RP 17-hexamethyl-4

SKU: 24895309894

4.1
USD100.00 USD141.00

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Description

17-hexamethyl-4

in these two cancer cell lines (H1417 and H146 cell lines)

CAS Number: 14080-23-0

the animals are euthanized

5-Azacytidine was intraperitoneally (IP) dosed to mice at 3 mg/kg once per day

Cl-amidine hydrochloride RP 17-hexamethyl-4Cl amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0. 8 M, 6. 2 M and 5. 9 M for PAD1, PAD3, and PAD4, respectively. Cl amidine hydrochloride induces apoptosis in cancer cells. Cl amidine hydrochloride induces microRNA (miR) 16 (miRNA 16, microRNA 16) expression and causes cell cycle arrest. Cl Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation,

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