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Fevipiprant demonstrates a favorable safety profile
proteasome-independent mechanism that influences remodelling of the cytoskeleton
Formula: C18H16NNaO5
2'-piperidin]-18-eneoxy]-5-{[(2S
OptoBI-1 is a photochromic TRPC3 agonist
R1498 do-tri-(carboxyethoxymethyl)-methane Fevipiprant demonstrates a favorable safetyR1498 is a multi target kinase inhibitor with anti angiogenic and anti proliferative activities. R1498 mainly targets targets such as Aurora kinase and VEGFR2, which are associated with tumor development. R1498 showed moderate in vitro growth inhibition in a variety of tumor cells, with IC50 values in the micromolar range. R1498 showed anti tumor efficacy superior to sorafenib in a variety of gastric cancer and hepatocellular carcinoma xenograft