CEP 1347 ITC Smiles: CC(C)(C)OC(=O)COCCOCCOCCCCCCOCC1C=CC=CC=1

Smiles: CC(C)(C)OC(=O)COCCOCCOCCCCCCOCC1C=CC=CC=1

AZ7550 inhibits DM antiproliferative cell line H1975

7-naphthyridin-4-yl)phenyl]methyl}piperazin-1-yl)pentyl]oxy}-4-(4-methyl-1

⁷]dodeca-1(9)

CAS Number: 61368-63-6

CEP 1347 ITC Smiles: CC(C)(C)OC(=O)COCCOCCOCCCCCCOCC1C=CC=CC=1CEP 1347, also called KT 7515, is an inhibitor of the c Jun N terminal kinase (JNK) signaling pathway, with an IC50 value for JNK1 activation of 20 2 nM in rat embryonic motoneurons . The JNK pathway, also known as the stress activated protein kinase (SAPK) pathway, is one of the signaling cascades that mediate the apoptotic death in response to a variety of stressful stimuli. JNK activation by phosphorylation is important for neuronal cell death