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acute administration of an intravenous ansofaxine solution does not induce the undesirable 90% decrease in extracellular 5-HT levels
which is significantly lower than that of 3-AP (Triapine
Smiles: CC(C)(OC1C=CC(Cl)=CC=1)C(O)=O
Smiles: COC1=CC(/C=C/C2C=CC(O)=CC=2)=CC=C1/C=C/C1C=CC(O)=CC=1
InChiKey: HIFJCPQKFCZDDL-GBSCXWAGSA-N
JP83 Catalog No.:M22642-C acute administration of an intravenousIC50: 14 nM for the human recombinant enzyme JP83 is an irreversible fatty acyl amide hydrolase (FAAH) inhibitor. The enzyme fatty acyl amide hydrolase (FAAH) is capable of hydrolyzing anandamide and other esters and amides with long unsaturated acyl chains, which is widely expressed in brain and other tissues. In vitro: JP83 was identified as an irreversible FAAH inhibitor of the carbamate class when it was tested using radiolabeled oleamide as the
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