5R)-4-hydroxy-3-(((E)-3-(4-hydroxy-3
InChiKey: OPEGAEBRVGIBAS-UHFFFAOYSA-N
7)43(53-31(5)59)46(63)57-25-36(60)22-38(57)45(62)51-24-32-8-10-34(11-9-32)42-28(2)52-26-66-42/h8-15
Smiles: [2H]C1([2H])C([2H])([2H])C([2H])([2H])N(C2CCN(CC2)C(=O)OC2C=C3C(CC)=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC3=CC=2)C([2H])([2H])C1([2H])[2H]
Smiles: OC(=O)[C@H]1O[C@@H](OC2C=C3SC(=C(C3=CC=2)C(=O)C2C=CC(=CC=2)OCCN2CCCCC2)C2C=CC(O)=CC=2)[C@H](O)[C@@H](O)[C@@H]1O
TC-N 22A Catalog No.:M18602-C 5R)-4-hydroxy-3-(((E)-3-(4-hydroxy-3TC N 22A is a potent, selective, orally active and brain permeable mGlu4 PAM with an EC50 of 9 nM in human mGlu4 expressing BHK cells. TC N 22A is less active (EC50>10 M) in agonist and PAM model at mGlu 1, 2, 3, 5, and 7 receptors. TC N 22A has the potential for research of CNS disease in vivo. Product information CAS Number: 1314140 00 5 Molecular Weight: 283. 35 Formula: C14H13N5S Chemical Name: (4Z) N (pyridin 2 yl) 5 thia 3,11,12