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Pifithrin-μ - CAS# 64984-31-2 262 CC(C)[C@H](NC(=O)OC)C(=O)N1CC2(C[C@H]1C1NC(=CN=1)C1=CC3=C(C=C1)C1=CC=C(C=C1C3(F)F)C1=CC3NC(=NC=3C=C1)[C@@H]1[C@@H]3C[C@@H](CC3)N1C(=O)[C@@H](NC(=O)OC)C(C)C)CC2

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Description

CC(C)[C@H](NC(=O)OC)C(=O)N1CC2(C[C@H]1C1NC(=CN=1)C1=CC3=C(C=C1)C1=CC=C(C=C1C3(F)F)C1=CC3NC(=NC=3C=C1)[C@@H]1[C@@H]3C[C@@H](CC3)N1C(=O)[C@@H](NC(=O)OC)C(C)C)CC2

Rucaparib shows binding affinity to eight other PARP domains

PubMed Central PMCID: PMC4543626

selective and orally active inhibitor of STAT3 with IC50 of 1

PF03394197

Pifithrin-μ - CAS# 64984-31-2 262 CC(C)[C@H](NC(=O)OC)C(=O)N1CC2(C[C@H]1C1NC(=CN=1)C1=CC3=C(C=C1)C1=CC=C(C=C1C3(F)F)C1=CC3NC(=NC=3C=C1)[C@@H]1[C@@H]3C[C@@H](CC3)N1C(=O)[C@@H](NC(=O)OC)C(C)C)CC2Pifithrin is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity. Product information CAS Number: 64984 31 2 Molecular Weight: 181. 21 Formula: C8H7NO2S Synonym: PFT 2 Phenylethynesulfonamide Chemical Name: phenylethynesulfonamide Smiles: NS(=O)(=O)C#CC1C=CC=CC=1 InChiKey: ZZUZYEMRHCMVTB UHFFFAOYSA N InChi: InChI=1S C8H7NO2S c9 12(10,11)7 6 8 4 2 1 3 5 8 h1 5H,(H2,9,10,11) Technical Data Appearance: Solid Power Purity: 98% (or

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