Gap19 amine A-D3 FE-202845) is a peripherally restricted

FE-202845) is a peripherally restricted and selective agonist of kappa opioid receptor (KOR)

DCH36_06 (25-50 mg/kg

20-heptaoxadocosan-22-yloxy)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9

Smiles: CC1=CC(=CC(=C1F)C(=O)NNS(=O)(=O)C1=CC(O)=CC=C1)C1C=CC=CC=1

CAS Number: 117091-64-2

Gap19 amine A-D3 FE-202845) is a peripherally restrictedGap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40 pannexin 1 hemichannels. Gap19 has protective effects against myocardial. Product information CAS Number: 1507930 57 5 Molecular Weight: 1161. 44