Inosinic acid 5403 JNJ-26483327 with TAPI-1 exerts less

JNJ-26483327 with TAPI-1 exerts less cell viability inhibition than Herceptin alone in both SKBR3 and BT474 cells

CAS Number: 111358-88-4

COC1=CC2=C(NC3=CC=C(Br)C=C3F)N=CN=C2C=C1OCC1CCN(C)CC1

Smiles: OC(=O)CCOCCN1C(=O)C=CC1=O

with an EC50 of 256 ± 40 nM being observed

Inosinic acid 5403 JNJ-26483327 with TAPI-1 exerts lessInosinic acid is an endogenous metabolite. Product information CAS Number: 131 99 7 Molecular Weight: 348. 21 Formula: C10H13N4O8P Chemical Name: {[(2R,3S,4R,5R) 3,4 dihydroxy 5 (6 oxo 6,9 dihydro 1H purin 9 yl)oxolan 2 yl]methoxy}phosphonic acid Smiles: OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CNC2=O InChiKey: GRSZFWQUAKGDAV KQYNXXCUSA N InChi: InChI=1S C10H13N4O8P c15 6 4(1 21 23(18,19)20)22 10(7(6)16)14 3 13 5 8(14)11 2 12 9(5)17 h2 4,6